Tazarotene, which is also known by the brand names Arazlo and Tazorac, is a powerful prescription retinoid that has been shown to build collagen, reverse fine lines and wrinkles, reduce discoloration from sun damaged skin and treat acne. It has also been shown to be effective in reducing the size of atypical melanocytes and keratocytes which are thought to be precursors to skin cancer. This medication has been shown in peer reviewed double blinded studies to be highly effective and is often used in conjunction with oral antibiotics to treat acne.
The most common side effects associated with this medication are itching, burning or stinging, dryness of the skin and mild redness and irritation. If these side effects persist or become worse, notify your doctor. It is important to avoid contact with your eyes, mouth and genitals when applying this medicine. If these areas do come into contact, rinse immediately with water. Do not use more than prescribed. This medication should not be used during pregnancy. Women who could become pregnant should have a negative pregnancy test within 2 weeks before starting this medication and should use reliable forms of birth control while taking it. It is unknown whether this drug passes into breast milk. Consult your doctor before breastfeeding.
Before using this medication, tell your doctor or pharmacist if you are allergic to tazarotene, other medications, foods or dyes, or if you have any other medical condition. Your doctor will tell you how much to apply and how often to use this medication. It is recommended that you wash your hands before and after handling this medication. During treatment, your skin will be more sensitive to sunlight and other sources of UV light. It is recommended that you wear clothing, wide-brimmed hats and use sunscreen with SPF 30 or higher when exposed to the sun.
After application, this medication is absorbed into the bloodstream and is metabolized in the liver to its active metabolite tazarotenic acid. This metabolite is eliminated from the body through the urine and feces. Depending on your response to treatment, this medication may be taken orally or topically.
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