Fenbendazole is an inexpensive broad-spectrum anthelminthic that has been shown to be effective against various parasites and tumors in both animals and humans. It is used to treat gastrointestinal parasites such as roundworms, hookworms, whipworms, and some tapeworms. It is also used to treat helminthic infections in cats and dogs, including cystic hydatid disease. In addition, it has anticancer properties. It has been shown to be more effective than chemotherapy at killing cancer cells, and it is less likely to cause chemo-resistance.
This drug is available in oral granules or as a liquid suspension and is given by mouth. The dosage varies according to the type of helminthic infection being treated, but is typically given by mouth once daily for 3 days. Alternatively, the granules may be mixed into the food for the animal. The liquid form is usually more convenient because it does not require shaking and can be administered directly to the gastrointestinal tract. The active ingredient is methyl 5-(phenylthio)-2-benzimidazolecarbamate (Sigma Catalog Number: 43210-67-9; Synonyms: Methyl 1-(phenylthio)-2-benzimidazolecarbamate, benzimidazole carbamate, and phenyl 2-benzimidazole carboxamide).
It has been shown to be very safe for human use, and its LD 50 in laboratory animals exceeds 10 g/kg. It is also well tolerated in animals when administered at labeled doses. It is particularly effective against ascarids, and has been shown to give high egg count reductions against tapeworms such as Necator americanus and Paragonimus westeri. It has also been found to be effective in treating the common hookworm Ascaris lumbricoides, giving high egg count reductions in both young and adult animals.
A recent study has found that fenbendazole can be used as an effective treatment for several types of cancer, including lymphoma and leukemia. It works by inhibiting the production of reactive oxygen species that damage cells. It also acts as an immunotherapy by stimulating the body’s natural immune response to kill cancer cells. It is a promising therapy for several types of cancer, but further research is needed to determine its effectiveness and safety.
Another potential cancer treatment is curcumin, a compound that has been shown to increase healthy levels of the p53 gene in cancer cells. It is derived from the spice turmeric, and is available as a supplement in powder form. It is also available in capsules from sanare lab fenbendazole, which are made of plant-based material.
It has been reported that fenbendazole prevents cancer cells from growing in a petri dish by blocking an enzyme called ATP citrate synthase, which is necessary for their proliferation. It is possible that this effect will be enhanced by combining it with other treatments, such as chemotherapy or radiation. Moreover, it is not known whether cancer cells will eventually become resistant to fenbendazole. This is a major advantage over many other cancer treatments, which often become ineffective over time because of resistance.